He is one of the Sweet Commanders of the Big Mom Pirates. Before his fight against Luffy, Katakuri had an unbeaten record, which was extremely impressive.
The leader of the Arlong Pirates, responsible for Nami's tragic backstory and an early antagonist in the series.
A member of the Cipher Pol 9 and one of the most formidable government agents in the series.
The self-proclaimed "God" of Skypiea, who possesses immense electrical powers.
A Yonko, one of the Four Emperors of the Sea, known for her terrifying power and insatiable hunger.
Kaido is the main antagonist of the Wano arc. Only a handful of characters have managed to hurt Kaido in a fight, which shows his insane resistance to Armament Haki.
The former leader of Baroque Works, a powerful and cunning antagonist during the Alabasta Arc.
A complex and ambitious pirate who becomes a major antagonist in the series.
Akainu is popular within the One Piece community for all the wrong reasons. Despite being a Navy Admiral, Akainu shows no real interest in protecting the people of the world.
It's impossible for fans to not remember the former King of Dressrosa. His appearance at Punk Hazard sent shivers down the spine of the entire G-5. While Doflamingo is not the most powerful villain in One Piece, he is certainly the most wicked one.